E-400, offered by Douglas Laboratories, is a powerful dietary supplement that provides superior antioxidant protection through its natural d-alpha tocopheryl acetate formula. Vitamin E is essential for the body as it acts as a potent antioxidant, protecting healthy cells from oxidative and free radical damage.

Free radicals are unstable chemicals that are produced during the body's metabolism and exposure to environmental sources like air pollution and cigarette smoke. While some free radicals are necessary for energy metabolism and immune function, an excessive amount can attack healthy cells and degrade their structure and function, particularly their membrane lipids, proteins, and nucleic acids.

Vitamin E plays a crucial role in protecting cell membranes, especially in red blood cells and tissues that are sensitive to oxidation, such as the lungs, eyes, and arteries. It effectively prevents the oxidation of unsaturated fatty acids by trapping free radicals, thereby stabilizing and safeguarding cell membranes.

Moreover, vitamin E shields the liver and other tissues from the harmful effects of toxicants, including mercury, lead, ozone, carbon tetrachloride, benzene, cresol, and various drugs. By providing antioxidant properties, vitamin E also supports normal immune function and prevents lipid peroxidation of blood lipoproteins, such as LDL-cholesterol.

Vitamin E encompasses eight compounds with varying levels of biological activity, including the alpha, beta, gamma, and delta forms of tocopherol and tocotrienol. Among these, the most biologically active is alpha tocopherol. E-400 specifically contains the acetate esterified form of the natural d-alpha tocopherol isomer, which occurs naturally in nature.

Notably, natural d-alpha tocopherol is more efficiently absorbed and has significantly higher bioavailability than synthetic dl-alpha tocopherol. Therefore, E-400 ensures optimal absorption and utilization of vitamin E in the body. It is important to consume E-400 along with dietary fat as vitamin E absorption is associated with fat absorption.

When absorbed, vitamin E is transported through the circulatory system via chylomicrons and then transferred to VLDL, LDL, and HDL particles. Various tissues accumulate vitamin E from these plasma lipoproteins, with the highest concentrations found in the liver and adipose tissues. Muscle also plays a significant role in storing vitamin E.

E-400 is an ideal dietary supplement for individuals looking to increase their intake of potent, natural vitamin E. By incorporating E-400 into your daily routine, you can enhance your body's antioxidant defense system and promote overall health and well-being.